Med1 | mediator complex subunit 1

GeneMGI:1100846Synonyms: DRIP205, Pparbp, +5 more

Physiological systems

19 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Reproductive system Integument Embryo Growth/size/body region Nervous system Vision/eye Mortality/aging

12 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:10Significant phenotypes

0Associated diseases

Expression examined in:73Adult tissues

29Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



embryonic lethality prior to tooth bud stage	1 supporting dataset	Med1^{tm3b(EUCOMM)Wtsi}	homozygote	E12.5	N/A ^*
abnormal placenta size	1 supporting dataset	Med1^{tm3b(EUCOMM)Wtsi}	homozygote	E12.5	N/A ^*
abnormal embryo size	1 supporting dataset	Med1^{tm3b(EUCOMM)Wtsi}	homozygote	E12.5	N/A ^*
pallor	1 supporting dataset	Med1^{tm3b(EUCOMM)Wtsi}	homozygote	E12.5	N/A ^*
small superior vagus ganglion	1 supporting dataset	Med1^{tm3b(EUCOMM)Wtsi}	heterozygote	Early adult	N/A ^*
hydrometra	1 supporting dataset	Med1^{tm3b(EUCOMM)Wtsi}	heterozygote	Early adult	N/A ^*
pale yolk sac	1 supporting dataset	Med1^{tm3b(EUCOMM)Wtsi}	homozygote	E12.5	N/A ^*
preweaning lethality, complete penetrance	1 supporting dataset	Med1^{tm3b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
abnormal eye morphology	1 supporting dataset	Med1^{tm3b(EUCOMM)Wtsi}	homozygote	E12.5	N/A ^*
enlarged uterus	1 supporting dataset	Med1^{tm3b(EUCOMM)Wtsi}	heterozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

Rows per page:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Med1.

Associated images

Loading...

Histopathology

There is no histopathology data found for Med1.

IMPC related publications

Loading...

External links

No external links available for Med1.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Med1^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Med1^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell
*Med1^{tm3a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Med1^{tm3b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Med1^{tm3e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell

My Genes